Lab Publications

• Lien WH, Vasioukhin V. (2008) αE-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic. J Cell Biol., Dec 15;183(6):989-97.

• Chevillet JR, Park GJ, Bedalov A, Simon JA, Vasioukhin V. (2008) Identification and characterization of small-molecule inhibitors of hepsin. Mol Cancer Ther. Oct;7(10):3343-51.

• Lien WH, Stepniak E, Vasioukhin V. (2008 ) Dissecting the role of cadherin-catenin proteins in developing mammalian epidermis. Proc Natl Acad Sci USA. Oct 7;105(40):15225-6.

• Lien WH, Klezovitch O, Null M, Vasioukhin V. alphaE-catenin is not a significant regulator of beta-catenin signaling in the developing mammalian brain. J Cell Sci. 2008 May 1;121(Pt 9):1357-62.

• Lee M, Vasioukhin V. (2008) Cell polarity and cancer - cell and tissue polarity as a non-canonical tumor suppressor. J Cell Sci. 121(8): 1141-1150

• Klezovitch O, Risk M, Coleman I, Lucas J, Null M, True L, Nelson PS, Vasioukhin V. (2008) A causal role for ERG in neoplastic transformation of prostate epithelium. Proc Natl Acad Sci USA. 105(6): 2105-10

• Nechiporuk T, Fernandez TE, Vasioukhin V. (2007) Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in dlg5(-/-) mice. Dev Cell. 13(3): 338-50

• Lien W-H, Klezovitch O, Vasioukhin V. (2006) Cadherin-catenin proteins in vertebrate development. Curr Opin Cell Biol. 18(5)

• Haegebarth A, Bie W, Yang R, Crawford SE, Vasioukhin V, Fuchs E, Tyner AL. (2006) Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine. Mol Cell Biol. 26(13): 4949-57

• Lien W-H, Klezovitch O, Fernandez T, Delrow J, Vasioukhin V. (2006) alphaE-catenin controls cerebral cortical size by regulating hedgehog signaling pathway. Science. 311(5767): 1609-1612

• Nechiporuk T, Vasioukhin V. (2006) Planar cell polarity planes inconveniences of cell divisions into a smooth morphogenic process. Dev Cell. 10(2): 153-154

• Vasioukhin V. (2006) Lethal giant puzzle of Lgl. Dev Neurosci. 28(1-2>: 13-24

• Vasioukhin V. (2004) Hepsin paradox reveals unexpected complexity of metastatic process. Cell Cycle. 3(11): 1394-7

• Klezovitch O, Chevillet J, Mirosevich J, Roberts RL, Matusik RJ, Vasioukhin V. (2004) Hepsin promotes prostate cancer progression and metastasis. Cancer Cell. 6(2), 185-195

• Klezovitch O, Fernandez TE, Tapscott SJ, Vasioukhin V. (2004) Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes & Development. 18(5): 559-571