The Diagnostic and Biomarkers Statistical (DABS) Center

Educational Materials

Pepe MS, Janes H, Alonzo T.
Statistical Evaluation of Medical Tests and Biomarkers for Classification
ASA Joint Statistical Meeting, Denver, CO, August 2008
Janes H, Pepe MS, Feng Z, Bossuyt P, Potter J.
Pivotal Evaluation of the Accuracy of a Classification Biomarker: The PRoBE Study Design
Fred Hutchinson Cancer Research Center, July 2008
Pepe MS.
Evaluating Markers with a View to Impact on Medical Decision Making
Fred Hutchinson Cancer Research Center, October 2008.
Pepe, MS.
Evaluating Risk Prediction Markers and Models (shortcourse)
Food and Drug Administration. September 2008
Pepe MS.
Summarizing the Performance of a Risk Prediction Marker
University of California San Francisco, October 2007.
Pepe MS.
Towards Standards for Design of Biomarker Accuracy Studies
Invited talk, FDA/Industry Statistics Workshop, Arlington, Virginia, September 2007
Jin Y, Zheng Y, Pepe MS.
Evaluating the ROC Performance of Markers for Future Events
Joint Statistical Meeting, Salt Lake City, UT, August 2007
Pepe MS, Alonzo T, Janes H.
Statistical Evaluation of Medical Tests and Biomarkers for Classification
ASA Joint Statistical Meetings, Salt Lake City, UT, July 2007
Pepe MS, Gu WJ, Huang Y, Feng Z.
Evaluating the Incremental Impact of a Risk Prediciton Marker
ASA Joint Statistical Meetings, Salt Lake City, UT, July 2007
Pepe MS.
Statistical Methods for Evaluating Tests and Biomarkers in Medicine (shortcourse)
IBC, Montreal. July 2006

Pepe, M. S.
The Statistical Evaluation of Medical Tests for Classification and Prediction. Oxford University Press, 2003.
"...[T]his is a timely book that appears to cover a gap in the existing literature...This book is well written." — Journal of the American Statistical Association 2005 100:705.
Also reviewed in Pharmaceutical Statistics ( 2003;2:305); Statistics in Medicine ( 2005;24:2582); Journal of Biopharmaceutical Statistics (2004;141103); Statistical Methods in Medical Research (2004;13:341)
Zhou, S. H., Obuchowski N. A. and McClish, D. K.
Statistical Methods in Diagnostic Medicine [Supplementary materials available]
"...the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students". — Zentralblat MATH 2003;1007(7).
Knotterus, A. (ed)
Evidence Base of Clinical Diagnosis BMJ Books, 2002.

"This is an important book." — Clinical Chemistry 2002;48:2084.

If you know of a relevant class that is not listed here, please forward information to Noelle Noble.

September 15 2008.
Pepe MS. Evaluating Risk Prediction Markers and Models
2008 FDA/Industry Statistics Workshop , Washington, DC.
September 17 2007.
Pepe MS. Shortcourse on evaluating diagnostics and biomarkers at FDA/Industry workshop
2007 FDA/Industry Statistics Workshop , Washington, DC.
July 2007.
Pepe MS, Janes HJ, and Alonzo TA. Statistical Evaluation of Medical Tests and Biomarkers for Classification (CE)
ASA Joint Statistical Meetings , Salt Lake City, Utah.
June 2007.
Pepe, MS, Etzioni RE and Janes HJ. Summer Institute in Statistical Genetics, Module 15, Evaluation of Biomarkers
University of Washington, Department of Biostatistics
Winter 2006/Spring 2007.
Pepe, MS. Biostatistics, Reading and Research Topics in Evaluation of Biomarkers.
University of Washington, Department of Biostatistics.
October 25 2006.
Janes, H. "Statistical Methods for Evaluating Tests and Biomarkers in Medicine"
Food and Drug Administration, Center for Devices and Radiological Health (CDRH)
Fall 2006.
Pepe, MS. Biostatistics, Reading and Research Topics in Evaluation of Biomarkers.
University of Washington, Department of Biostatistics.
July 2006.
Pepe, MS. Statistical Methods for Evaluating Tests and Biomarkers in Medicine.
International Biometrics Conference, Montreal, Canada.