Our publications

2010

• Emerman M, Malik HS (2010) Paleovirology-- modern consequences of ancient viruses. PLoS Biology 8: e1000301. (Essay) Abstract | Full text
  

2009

• Oliver PL*, Goodstadt L*, Bayes JJ, Birtle Z, Roach KC, Phadnis N, Beatson SA, Lunter G, Malik HS, Ponting CP (2009) Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa. PLoS Genet. 5: e1000753. Abstract | Full Text
  
• Moran JV, Malik HS (2009) Diamonds and rust: how transposable elements influence mammalian genomes. EMBO Rep. 10: 1306-10. (Meeting Report) Abstract | Full Text
  
• Bayes JJ, Malik HS (2009) Altered heterochromatin binding by a hybrid sterility protein in Drosophila sibling species. Science 326: 1538-41. Abstract | Full Text
  
• Vermaak D, Malik HS (2009) Multiple roles for heterochromatin protein 1 (HP1) genes in Drosophila. Annu. Rev. Genet. 43: 467-92. (Review) Abstract | Full Text
  
• Elde NC, Malik HS (2009) The evolutionary conundrum of pathogen mimicry. Nat. Rev. Microbiol. 7: 787-97. (Review) Abstract | Full Text
  
• Malik HS, Henikoff S (2009) Major evolutionary transitions in centromere complexity. Cell 138: 1067-82. (Review) Abstract | Full Text
  
• Vermaak D, Bayes JJ, Malik HS (2009) A surrogate approach to study evolution of non-coding DNA elements that organize eukaryotic genomes. J. Hered. 100: 624-636. (Review) Abstract | Full Text
  
• Malik HS (2009)  The centromere-drive hypothesis: a simple basis for centromere complexity. Prog. Mol. Subcell. Biol. 48: 33-52 (Review, also published as a book chapter in “Centromere-Structure and Evolution”, ed: Durdica Ugarkovic, Springer-Verlag Publishing, Series). Abstract | Full Text
  
• Smith EE, Malik HS (2009) The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions. Genome Res. 19: 850-858. Abstract | Full Text
  
• Tareen SU, Sawyer SL, Malik HS, and Emerman M (2009) An expanded clade of rodent Trim5 genes Virology. 15: 473-83 Abstract | Full Text
  
• Elde NC, Child SJ, Geballe AP, and Malik HS (2009) Protein kinase R reveals an evolutionary model for defeating viral mimicry. Nature 457: 485 - 489 Abstract | Full Text
  
• LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, Strebel K, Wain-Hobson S, Yu XF, Yuhki N, Harris RS (2009) Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins. J. Virol. 83: 494-7 (Guest Commentary) Abstract | Full Text   

2008

• OhAinle M, Kerns JA, Li MM, Malik HS, Emerman M (2008) Antiretroelement activity of APOBEC3H was lost twice in recent human evolution. Cell Host Microbe 4: 249-59. Abstract | Full Text
  
• Bayes JJ, Malik HS (2008) The evolution of centromeric DNA sequences. Encyclopedia of Life Sciences, Wiley Publishing Co. DOI: 10.1002/9780470015902.a0020827 (Review, also published in “The Handbook of Human Evolution”, ed: David N. Cooper and Hildegard Kehrer-Sawatzki, Wiley Publishing Co.) Abstract | Full Text
  
• Kerns JA, Emerman M, and Malik, HS (2008) Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein. PLoS Genetics 4: 150-158. Abstract |  Full text

2007

• Sawyer SL, Emerman M, and Malik, HS (2007) Discordant Evolution of the Adjacent Antiretroviral Genes TRIM22 and TRIM5 in Mammals. PLoS Pathogens 3: 1918-1929.  Abstract  |  Full text
  
• Rodriguez MA*, Vermaak D*, Bayes JJ*, and Malik HS (2007) Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila melanogaster. PNAS 104: 15412-15417 Abstract  |  Full text
  
• Wiggins BL, and Malik HS (2007) Molecular evolution of Drosophila Cdc6, an essential  DNA replication-licensing gene, suggests an adaptive choice of replication origins. Fly 1: 155-163. Abstract  |  Full text
  
• Kaiser SM, Malik HS, Emerman M (2007) Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein. Science 316 Jun 22(5832):1756-8.  Abstract  |  Full text
  
• Malik HS (2007) Genes get diabolical. Nat Genet. 39(5):577. (Book Review) Full text

2006

• Sawyer SL, Malik HS (2006) Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis. Proc. Natl. Acad. Sci. USA 103: 17614-17619. Abstract  |  Full text
  
• Malik HS (2006) A hitchiker's guide to survival finally makes CENs. J. Cell Biol. 174: 747-9. (Comment) Abstract  |  Full text
  
• Malik HS, Bayes JJ (2006) Genetic conflicts during meiosis and the evolutionary origins of centromere complexity. Biochem. Soc. Trans. 34: 569-573. (Review) Abstract  |  Full text
  
• Ohainle M, Kerns JA, Malik HS, Emerman M (2006) Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H. J. Virol 80 3853-62. Abstract  |  Full text
  
• Sawyer SL, Wu LI, Akey JM, Emerman M*, and Malik HS* (2006) High-Frequency Persistence of an Impaired Allele of the Retroviral Defense Gene TRIM5α in Humans. Curr. Biol. 16: 95-100. Abstract  |  Full text
  
• Cervantes MD, Xi X, Vermaak D, Yao MC*, Malik HS* (2006) The CNA1 Histone of the Ciliate Tetrahymena thermophila Is Essential for Chromosome Segregation in the Germline Micronucleus. Mol Biol Cell. 17: 485-97. Abstract  | Full text

2005

• Malik HS, Henikoff S(2005) Positive Selection of Iris, a Retroviral Envelope-Derived Host Gene in Drosophila melanogaster. PLoS Genetics 1: e44. Abstract | Full Text | Figure
  
• Vermaak D, Henikoff S, Malik HS (2005) Positive Selection Drives the Evolution of rhino, a Member of the Heterochromatin Protein 1 Family in Drosophila melanogaster. PLoS Genetics 1: e9. Abstract | Full Text
  
• Malik HS (2005) Mimulus finds centromeres in the driver's seat. Trends Ecol. Evol. 20: 151-4. (Research Focus) Abstract | Full text
  
• Sawyer SL, Wu LI, Emerman M, Malik HS (2005) Positive selection of primate TRIM5α identifies a critical species-specific retroviral restriction domain. Proc. Natl. Acad. Sci. USA 102: 2832-7. Abstract | Full text
  
• Malik HS (2005) Ribonuclease H evolution in retrotransposable elements. Cytogen Genome Res. 110: 392-401. (Review, also published separately as a book, “Retrotransposable Elements and Genome Evolution” ed: J. N. Volff) Abstract | Full text

2004

• Sawyer SL, Emerman M, Malik HS (2004) Ancient adaptive evolution of the primate antiviral DNA editing enzyme, APOBEC3G. PLoS Biology 2: e275. Abstract | Full Text

2003

• Malik HS, Henikoff S (2003) Phylogenomics of the nucleosome. Nat. Struct. Biol. 10: 882-91. (Review) Abstract | Full text

Update in progress! Last updated March 10, 2010