Liu, Y, Warfield, L., Zhang, C., Luo, J., Allen, J., Lang, W.H., Ranish, J, Shokat, K.M., and S. Hahn (2009) Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex. Mol Cell Biol in press.
Mohibullah, N and Hahn S. (2008) Site-specific crosslinking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3. Genes Dev, 22:2994-3006.
Hahn S. (2008) Transcriptional Regulation (Meeting Review) EMBO Reports 9:612-619.
Lariviere, L., Seizl, M., van Wageningen, S., Rother, S., van de Pasch, L., Feldmann, H., Strasser, K, Hahn, S., Holstege, F.C.P., and P. Cramer (2008). Structure-system correlation identifies a gene regulatory Mediator Submodule. Genes Dev 22:872-877. PDF
Kim, B. Nesvizhskii, A.I., Rani, P.G., Hahn, S., Aebersold, R., and Ranish, J.A. (2007). The transcription elongation factor TFIID is a component of RNA polymerase II preinitiation complexes. Proc Natl Acad Sci USA 104:16068-16073. PDF
Chen H-T., Warfield, L, and Hahn, S. (2007). The positions of TFIIF and TFIIE in the RNA Polymerase II transcription Preinitiation Complex. Nat Struct Mol Biol. 14:696-703. PDF Supplementary Material
Kanin, E.I, Kipp, R.T., Kung, C., Slattery, M., Viale, A., Hahn, S., Shokat, K.M., and Ansari, A.Z. (2007). Chemical inhibition of the TFIIH associated kinase Cdk7/Kin28 does not impair global gene expression. Proc Acad Sci USA 104:5812-5817.
Miller, G., and Hahn, S. (2006) A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex. Nat. Struct. Mol. Biol., 13:603-610. PDF Supplementary Material
Reeves, W. M and Hahn S. Targets of the Gal4 transcription activator in functional transcription complexes. (2005) Mol Cell Biol., 25:9092-9102.
Fishburn, J., Mohibullah, N., and Hahn, S. (2005). Function of a eukaryotic transcription activator during the transcription cycle. Mol. Cell., 18:369-378.
Chen, H-T., and Hahn S. (2004). Mapping the location of TFIIB within the RNA Polymerase II Transcription Preinitiation Complex: A model for the Structure of the PIC Cell 119:169-180.
Ranish, J.A., Hahn, S., Lu, Y, Yi, E.C., Li, X-j, Eng, J, and Aebersold, R. (2004). Identification of TFB5, a new component of general transcription and DNA repair factor IIH. Nature Genetics 36:1-7.
Warfield, L, Ranish, J.A. and S. Hahn (2004). Positive and negative functions of the SAGA complex mediated through interaction of Spt8 with TBP and the N-terminal domain of TFIIA. Genes Dev. 18:1022-1034.
Hahn, S. (2004). Structure and Mechanism of the RNA Polymerase II transcription machinery (Review). Nat Struct Mol Biol. 11:394-403. PDF
Liu, Y, Kung, C., Fishburn, J., Ansari, A.Z., Shokat, K.M., and Hahn, S. (2004). Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the Scaffold Complex. Mol Cell Biol. 24:1721-1735.
Rani, G., Ranish, J.A., and Hahn, S. (2004). The Pol II-TFIIF and Pol II-Mediator complexes: the major stable RNA Polymerase II complexes and their activity in transcription initiaiton and reinitiation. Mol Cell Biol 24:1709-1720.
Chen, H-T. and Hahn, S. (2003). Binding of TFIIB to RNA Polymerase II: Mapping the Binding Site for the TFIIB Zinc Ribbon Domain within the Preinitiation Complex. Mol Cell12:437-448.
Reeves, W.M. and Hahn, S. (2003). Activator-Independent functions of the yeast mediator Sin4 complex in Preinitiation Complex Formation and Transcription Reinitiation. Mol Cell Biol. 23:349-358.
Liu, Y., Ranish, J.A., Aebersold, R., and Hahn, S. (2001). Yeast nuclear extract contains two major forms of RNA polymerase II Mediator complexes. (2001). J. Biol. Chem 276:7169-7175.
Yudkovsky, N., Ranish, J.A., and Hahn S. (2000). A transcription reinitiation intermediate that is stabilized by activator. Nature 408:225-229.
Hahn, S. and Roberts, S. (2000). The zinc ribbon domains of the general transcription factors TFIIB and Brf: Conserved functional surfaces but different roles in transcription initiation. Genes and Dev. 14:719-730.
Yudkovsky, N., Logie, C., Hahn, S., and Peterson, C.L. (1999). Recruitment of theSWI/SNF chromatin remodeling complex by transcriptional activators. Genes and Dev. 13:2369-2374.
Hahn, S. (1998). Activation and the role of reinitiation in the control of transcription by RNA Polymerase II. Cold Spring Harbor Symp. Quant. Biol. 63:181-188.
Hahn, S. (1998). The role of TAFs in RNA Polymerase II Transcription. Cell 95:579-582.
Colbert, T., Lee, S., Schimmack, G., and Hahn, S. (1998). Architecture of protein and DNA contacts within the TFIIIB-DNA complex. Mol. Cell. Biol. 18:1682-1691.
Geiger, J.H., Hahn, S., Lee, S., Sigler, P.B. (1996). The crystal structure of the yeast TFIIA/TBP/DNA complex. Science, 272:830-836.
Lee, S. and Hahn, S. (1995). Model for binding of transcription factor TFIIB to the TBP-DNA complex. Nature, 376:609-612.
Kang, J.J., Auble, D.T., Ranish, J.A., and Hahn, S. (1995). Analysis of the yeast transcription factor TFIIA: distinct functional regions and a polymerase II-specific role in basal and activated transcription. Mol Cell Biol. 15:1234-1243.
Auble, D.T., Hansen, K.E., Mueller, C.G.F., Lane, W.S., Thorner, J., and Hahn, S. (1994). Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism. Genes and Development 8:1920-1934.
Kim, Y., Geiger, J.H., Hahn, S. and Sigler, P.B. (1993). Crystal structure of a yeast TBP/TATA-box complex. Nature 365: 512-520.
Colbert, T. and Hahn, S (1992). A yeast TFIIB related factor involved in RNA polymerase III transcription. Genes and Dev. 6: 1940-1949.
M.C. Schultz, R.H. Reeder, and S. Hahn (1992). Variants of the TATA-binding protein can distinguish subsets of RNA polymerase I, II, and III promoters. Cell: 69, 697-702.
J. Ranish, W.S. Lane, and S. Hahn (1992). Isolation of two genes that encode subunits of the yeast transcription factor IIA. Science 255: 1127-1128.
S. Hahn, S. Buratowski, P.A. Sharp, L. Guarente (1989). Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions. Cell 58:1173-1181
Ranish, J.A., Yudkovsky, N., and Hahn, S. (1999). Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB Genes and Dev. 13:49-63.
S. Hahn, S. Buratowski, P.A. Sharp, L. Guarente (1989). Identification of a yeast protein homologous in function to the mammalian general transcription factor, TFIIA. EMBO J. 8:3379-3382.
S. Buratowski, S. Hahn, P.A. Sharp, L. Guarente (1988) Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature 334:37-42.
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