Publications

Oesterle EC, et al. p27 (Kip1) is required to maintain proliferative quiescence in the adult cochlea and pituitary. Cell Cycle,. Apr 15, 2011, 10(8).

Kuppers DA, et al. Effect of Xpcl1 Activation and p27 Loss on Gene Expression in Murine Lymphoma. PLoS One. Mar 11, 2011; 6(3).

Lin CH, et al.  Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc. PLoS One. Nov 13, 2009; 4(11):e7839.

Glover CE, et. al.  Endocrine dysfunction in p27Kip1 deficient mice and susceptibility to Wnt-1 driven breast cancer. Carcinogenesis. June 2009; 30(6):1058-63.

Garrett-Engele CM, et al. A mechanism misregulating p27 in tumors discovered in a functional genomic screen.  PLoS Genet. Dec 2007; 3(12).

Chien WM, et al. Differential gene expression of p27Kip1 and Rb knockout pituitary tumors associated with altered growth and angiogenesis. Cell Cycle. 2007 6(6):750-7.

Chien WM, et al. Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1. Proc Natl Acad Sci USA. 2006 103(11):4122-7.

Walkley CR,etal. Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells. Nat Cell Biol. 2005 Feb;7(2):172-8.

Hwang HC,et al. Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11293-8.

McArthur GA, et al. MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity. Mol Cell Biol. 2002 May;22(9):3014-23.

Beier R, et al. Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events. EMBO J. 2000 Nov 1;19(21):5813-5823.

Levine EM, et al. p27(Kip1) regulates cell cycle withdrawal of late multipotent progenitor cells in the mammalian retina. Dev Biol. 2000 Mar 15;219(2):299-314.

Coats S, et al. A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells. Curr Biol. 1999 Feb 25;9(4):163-73.

Cheng M, et al. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 1999 Mar 15;18(6):1571-83.

Lowenheim H, et al. Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4084-8.

Hiromura K, et al. Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1). J Clin Invest. 1999 Mar;103(5):597-604.

Fero ML, et al. The murine gene p27Kip1 is haplo-insufficient for tumour suppression. Nature. 1998 Nov 12;396(6707):177-80.

Durand B, et al. p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation. Curr Biol. 1998 Apr 9;8(8):431-40.

Ophascharoensuk V, et al. The cyclin-dependent kinase inhibitor p27Kip1 safeguards against inflammatory injury. Nat Med. 1998 May;4(5):575-80.

Fero ML, et al. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell. 1996 May 31; 85(5): 733-744.

Morgan WF, et al. Inducible expression and cytogenetic effects of the EcoRI restriction endonuclease in Chinese hamster ovary cells. Mol Cell Biol.1988 Oct;8(10):4204-11.

Morgan WF, et al. Induced sister chromatid exchange frequency is not increased in homogeneously staining regions that contain amplified genes. Cancer Genet Cytogenet. 1987 Jun;26(2):245-51.

Morgan WF, et al.  Spontaneous and 3-aminobenzamide-induced sister-chromatid exchange frequencies estimated by ring chromosome analysis.  Mutagenesis. 1986 Nov;1(6):453-9.